41 results
Objective: 1. To determine protein balance in septic, critically ill children at baseline and during a Hyperinsulinemic Euglycemic Clamp, while receiving standard or high protein intake based on age group; 2. To assess insulin sensitivity and…
It is expected that the drink will contribute to an improved postprandial glycaemic response and to an increase of satiety in subjects with type 2 diabetes mellitus.
Objectives: 1. To investigate the added effects of eplerenone on top of ACEi, with and without dietary sodium restriction, on residual albuminuria, hypertension, and tubular injury markers, in patients with diabetic nephropathy; 2. To investigate…
Deep brain stimulation influences the HPA axis and glucose- and lipid metabolism in patients with obsessive compulsive disorder (OCD).
Acute challenges with cocaine and cannabis will induce two opposing dopaminergic states in the brain. Cocaine will stimulate dopamine release leading to hyperdopaminergia whereas cannabis will reduce central dopamine levels resulting in…
The main of the study is to gain more information about the sedative effects of two doses (20 and 40 mg) of bilastine and to assess the effect of repeated dosing on the road driving ability. It is expected that no differences will be detected…
In the present study we will investigate the efficacy of Lybridos in one group of subjects with FSD in the laboratory. We will measure subjective, physiological and neuropsychological measures of sexual functioning in the Emotional Brain laboratory…
Evaluation of difference in tolerability and efficacy as measured by bonemarkers between generic versus brand alendronate in postmenopausal women with osteoporosis.
The behavioural effects of an antihistamine is apparent in the evening after an evening dose, but will be smaller in the morning after a morning dose condition due to the excessive release of histamine shortly after awaking.
Preceding dwell with icodextrin does not influence the results of the 3.86% glucose PET in CAPD.
Administration of a lipid emulsion consisting of long-chain triglycerides (LCT-trial) in non-trained individuals, will induce insulin resistance due to increased DAG accumulation and subsequent activation of the PKC pathway in skeletal muscle.…
Our hypothesis is that alteration of the position of the postprandial acid pocket leads to less acid reflux events. The gastrokinetic properties of azithromycin might enable this effect, as was shown in the study by Mertens et al. {mertens}This…
We hypothesize that the hypothalamic neuronal activity in response to water is different in response to a mixed meal.
Dronabinol impairs driving performance in light cannabis users, but not in heavy users, because of tolerance to the impairing effects.
We hypothesize that the electric device offers a more standardized way of embryo transfer, resulting in higher pregnancy rates.
1. Modafinil influences fatigue, cognitive functioning, and quality of life of LGG patients; 2. There is a correlation between (changes in) fatigue, cognition, and quality of life on the one hand, and functional connectivity in the brains of LGG…
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The quality of taste affects sensory specific satiety. This is shown in both liking and wanting processes.
We hypoothesize that the effect that a single dose of montelukast has on exercise induced bronchoconstriction correlates with the effect it has after 8 weeks of treatment.
Hepatic insulin sensitivity increase after dopamine depletion, with a-methylparatyrosine (AMPT).