34 results
The aim of this study is to improve 6MP treatment in pediatric leukemia patients, by developing and licensing a pediatric liquid formulation of 6MP, assessing its stability and bioequivalence, and ensuring a nationwide introduction of the new…
The primary objective of the study is to determine the gain in effectiveness of TE compared with P when applied to remove excess iron during maintenance therapy of HH patients.
In this study we will be looking at the effects of the different administration routes on release of satiety hormones by the small intestine.
The aim of this study is to determine whether subcutaneous administration of insulin detemir, as compared to NPH insulin, leads to a more pronounced effect on brain glucose metabolism and blood flow in brain regions associated with appetite…
The primary objective of this study is to determine whether ACE inhibition results in an improvement of microvascular glycocalyx-thickness in patients with type 1 diabetes. The secondary objectives are to investigate whether this (hypothesized)…
The primary objective is to examine whether vardenafil (a PDE-5 inhibitor) can improve the cognition of healthy young volunteers. Secondary, we will assess the effects of vardenafil on electrophysiological correlates of cognition.
The primary objective is to determine the effect of co-administration of telepravir, given as 2 tablets of 375 mg every 8 hours and DRV/rtv or fAPV/rtv on the amount of telaprevir and DRV/rtv or fAPV/rtv in the body. The secondary objective is to…
The objectives are:1. the effect of steady state concentrations of voriconazole and fluconazole on the steady-state pharmacokinetics of TMC125,2. the effect of steady-state concentrations of TMC125 on the steady-state pharmacokinetics of…
The objective is to study whether saturated fatty acids induce a different postprandial change in inflammatory markers than cis-polyunsaturated fatty acids.
to investigate whether showering shortly after Androgel application adversly affects plasma testosterone levels.
The purpose of this study is to investigate the acute effects of a single bout of WBV on spasticity of calf muscle in stroke patients.
The major research objective is:- to examine whether elevation of plasma FFAs results in cardiac lipid accumulation and whether this influences cardiac function negatively.Additional research objective: - to examine whether cardiac lipid content is…
The primary objective of this study is to evaluate the effect of colostrum supplementation on the immune response after intense strenuous exercise.The secondary objective is to study the effect of intense strenuous exercise - and its possible…
The main objective is to quantify the effect of high saltiness level versus low saltiness level in tomato soup on ad libitum intake.
The objective of the study is to investigate the effect of PEEP ventilation with or without a recruitment maneuver on right ventricular afterload in infants undergoing cardiac surgery.
The primary objective of this study is to compare the stent migration rate of two metal expandable stents in patients with benign esophageal conditions.The secondary objectives are:• To compare the technical outcome.• To compare the functional…
The primary objective is to examine whether a memory impairment as a result of biperiden treatment (cholinergic M1 antagonist) will be increased by acute tryptophan depletion (ATD, a drink that decreases serotonin synthesis). In other words, we will…
To investigate the difference between two meals (high in protein vs. high in carbohydrates) on the endothelial function?
The aim is to learn more about the neural bases of speech comprehension in difficult listening situations by identifying whether the left ventral premotor cortex is essential for processing the highly variable acoustic signal.
Evaluation of the effect of treatment with the Meniett in patients with unstable Menière*s disease.