24 results
The purpose of the study is to investigate how quickly and to what extent BAY 1834845 is absorbed and eliminated from the body (this is called pharmacokinetics). In both study parts it will also be investigated to what extent BAY 1834845 is…
The objective of the study is to find answers on the research question: does activation of descending nociceptive inhibitory mechanisms via central pain medication lead to changes in kinematic and/or muscular changes in shoulder function?
What is the influence of the Rebound Hip and Newport 4 hip brace on restricting the movements that are associated with hip dislocation after at total hip replacement.
The objective of this pilot study is to demonstrate that NAVA ventilation is superior compared to pressure support and pressure control ventilation in work of breathing (expressed as pressure-time product) patient ventilator synchrony and other…
The primary objective in this study is to evaluate effectiveness of optimized high cervical epidural neurostimulation against placebo-stimulation in patients with intractable cervicogenic headache in a neurostimulation trial.
The primary aim of the study is (i) to assess the effect of a soft brace on pain, knee stability and activity limitations. Secondary aims are (ii) to assess the difference in effect of two knee soft braces (i.e., non-tight and tight) on pain and…
The objective of this feasibility study is compare the smart AFO + standardized shoes to subjects* own AFO + own shoes. Subjects* experiences with the orthotic devices will be evaluated and points for improvement will be asked. Subjects* performance…
The purpose of the study is to investigate the absorption, distribution and elimination of GLPG1972 administered as oral solution compared to GLPG1972 administered as oral tablets (this is called bioavailability). Furthermore, the effect of food on…
The objective of this study is to test whether meat structure plays an important role in protein digestion, to maximise the amino acid availability and to stimulate the muscle protein growth in elderly people.
The purpose of the study is to investigate whether the cyclodextrin added to the cholecalciferol formulation has an effect on the vitamin D3 availability in the body. Thus, it will be investigated if concentrations of vitamin D3 that are found in…
To determine whether the intake of minced beef is equally effective as ingestion of a bovine milk protein beverage in stimulating post resistance exercise muscle protein synthesis rates in young men.
Part 1: Quantification of individual patient-prosthesis interactions- Determination of the instantaneous effect of prosthetic knees with variable biomechanical properties on the gait pattern of PULAs (Part Ia). - Determination of the influence of…
To optimize ventilator support in critically ill patients admitted to the intensive care unit by monitoring electromyography of the respiratory muscles.
The aim of this study is to investigate the efficacy, accuracy and patient satisfaction of intra-articular injections in the osteo-arthritic ankle joint using the traction device compared to the conventional method of injecting.
To assess the effect of adalimumab and rituximab on the safety and efficacy of vaccination with T cell-dependent and T cell-independent primary and recall antigens.
(1) To analyze differences in pain and function in patients with CMC-1 osteoarthritis after application of a custom made orthosis and an off-the-shelf orthosis (Push brace) (2) To measure compliance and factors influencing compliance with splint…
The primary objective(s) of this study is:- To determine the relative bioavailability of etoricoxib 120 mg tablets manufactured at Frosst Iberica, Spain and Elkton, VA, USA.
Main study: to examine whether low dose GC therapy is more effective via the oral route compared to the parenteral route.Dose finding study (pilot study): to examine which oral GC dose is needed for a noticeable decrease in Erythrocyte Sedimentation…
The primary objective is to quantify the postprandial area under the curve (iAUC), the maximal level (Cmax) and the time profile (Tmax) of blood amino acids after ingestion of milk protein, micellar casein, pea protein, and a milk protein-pea…
To assess whether co-ingesting keto-analogues of branched-chain AAs along with protein during HD can attenuate HD-initiated muscle catabolism.