23 results
To evaluate the effect of parenteral supplementation of fishoil based emulsion (rich in omega-3 fatty acids) compared with a soy bean oil emulsion (rich in omega-6 fatty acids) on the leukocyte functions (amongst others production of TNF-α and other…
Since imatinib easily and rapidly dissolves at pH 5.5 or less, a lack of gastric acid secretion might be causing the decreased exposure in the patients that underwent major gastrectomy. Therefore we would like to study if the exposure to imatinib in…
To investigate whether two newly developed, potato based LOPG drinks with a different osmolarity and volume taken before exercise, differently affect gastric distress after both a short and long term exercise, running performance, and the rate of…
Specific research objectives:Investigate the effect of orally administered citrulline at:- Circulation of gastrointestinal (GI) system- The occurrence of GI damage, liver and kidneys- The GIpermeability - Production of amino acids- Endothelial…
Primary Objective: - To investigate the efficacy of Namisol® after a single dose of Δ9-THC on the experienced pain intensity (measured by the VASpain in rest and on movement) in patients with chronic pancreatitis.Secondary Objectives:- To…
Primary objectiveTo determine the effect of multiple dose OME on the pharmacokinetics (AUC0-8h, Cmax, C8h) of BOC.Secondary objectives:To determine the effect of steady state BOC on the pharmacokinetics (AUC0-8h, Cmax, C8h) of multiple dose OME.To…
To compare the additional diagnostic yield obtained by using the PeerScope System* extended view vs. the diagnostic yield obtained by the Standard view colonoscopy.In addition, time measurements including time to cecum, time for withdrawal and…
The purpose of this prospective randomized controlled trial is to demonstrate that the EsophyX-TIF procedure will be more effective than PPI therapy as a short and long-term treatment of GERD.
With this study we will investiagate the superiority of fecal clysma therapy (n=34 patients) above conventional therapy with the antibiotic vancomycin (n=34 patients) or bowellavage with conventional antibiotic therapy (n=34 patients).
1) to compare NBI and standard White Light Endoscopy (WLE) for the detection of neoplasia during colonoscopic surveillance of patients with longstanding UC2) To determine the accuracy of Kudo*s classification in distinguishing neoplastic from non…
The primary objective of this clinical study is to compare the incidence of post-repair wound related complications, including hernia occurence/reccurence between challenging abdominal wall defects repaired with Strattice Reconstructive Tissue…
Evaluation of the effectiveness of a new system HD2/NBI2 to improve the detection of colorectal neoplastic lesions during colonoscopy in comparison to the former generation with currently highest share of the installed base (nonHD-nonNBI system i.e…
The effect of a high-fat breakfast on intestinal permeability will be examined in lean and obese men to see if a fat load can induce increased intestinal permeability and it is a feasible challenge test to investigate effects of foods / ingredients…
To investigate the influence of left and right lateral position on the onset of TLESRs and GER and the underlying mechanisms during and after a test meal in GERD patients compared to healthy controls.
The aim of the study is to compare magnesiumhydroxide and polyethylene glycol/electrolytes with regard to the prevention of constipation and side-effects in palliative care cancer patients starting with opioids.
Our Objective is to show that the administration of prokinectics leads to an altered position of the acid pocket scintigraphically, and it thereby changes the rate of postprandial acid reflux episodes.
1. To investigate different modes of allergen administration to the esophageal wall, by testing the effect on visible mucosal changes2. To investigate which immune cells become activated after allergen provocation 3. To investigate whether the…
The study focuses on children and young people with IBD from 6-18 years old. These children have lower levels of physical activity and a limited endurance compared to healthy children. Through this research we want to improve the endurance of…
Primary objective:- To demonstrate that CT-P13 is noninferior to Remicade at Week 6 (Dose 3), in terms of efficacy, asdetermined by the Crohn*s Disease Activity Index (CDAI)-70 response rate.Secondary objectives:-To evaluate long-term secondary…
The effect of pelvic floor physiotherapy with biofeedback in patients with anal fissure and pelvic floor dysfunction.