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The Internet 'Self-Examination Therapy' (SET) on anxiety, depression and burn-out wil be effective in reduction of complaints (depression, anxiety, burn-out).
An upfront RBCT aiming at low-normal Hb levels will ameliorate anemia-caused tumor hypoxia-related resistance to chemotherapy before the start of chemotherapy and may decrease secondary anemia-induced endogenous release of cytokines like VEGF,…
A large proportion of chronic patients with complex regional pain syndrome type 1 suffer from both neuropathic pain and dystonia. Findings from neurophysiological and intrathecal baclofen studies highlight an impaired inhibitory neurotransmission.…
1. We hypothesize that children with solitary encopresis have a disturbed compensation reflex, eventually combined with aberrant huge rectal contractions; 2. We hypothesize that in children with solitary encopresis loperamide rectally given, will…
Patients with high scores on anxiety and neuroticism will experience a lower Quality of Life after breast conserving therapy compared to modified radical mastectomy.
Can mortality in ICU-patients be reduced by using SDD or SOD as infection prevention measure, without increasing the development of antibiotic resistance.
Administration of Ibopamine hydrochloride eye drops restores intraocular pressure in patients with hypotony following vitreoretinal surgery or uveitis.
A combination of Lycopene and Vitamin E decreases PSA progression.
Inhalation of rhDNase after airway clearande therapy (ACT) increases the expiratory flow at 25% of the actual forced vital capacity (MEF25) compared to inhalation of rhDNase before ACT.
Hypothesis: The implementation of microarray diagnostics is feasible in general practice in community hospitals.
About 6% of the population between 3 and 79 years suffers each year of a B.pertussis infection, also pregnant women. These women are a source of infection for their newborn babies.
1. Cysteine is an essential amino acid for newborn preterm infants; 2. Cysteine requirements change rapidly with postnatal age; 3. The change in cysteine requirement with age is based upon cystathionase activity; 4. Intestinal cystathionase activity…
In the pathogenesis of medullary thyroid carcinoma a mutation of the RET thyrosine kinase system plays an essential role. In animal models the thyrosine kinase inhibitor imatinib showed tumor regression. So a Phase-2 study in patients with…
1. TGF-beta protects childhood cancer patients against chemotherapoy induced damage in the digestive tract; 2. TGF-beta can safely be administered to childhood cancer patients.
1. Welke rokers hebben baat bij welke transmurale “stoppen-met- roken- interventiestrategie”?; 2. Wat zijn de effecten van de verschillende “stoppen-met- roken- interventiestrategieën”?
Speech understanding with a speech processor fitted using the parametric fitting procedure and the recipient's own fine-tuning is as good as with a conventional fitting. The parametric fitting is more patient friendly and less time-consuming.
An early intervention with low-dose aspirin in asymptomatic diabetic subjects attenuates progression of atherosclerosis, by decreasing inflammation and coagulation.
There are predictive markers of treatment response (or non-response) at baseline or during early beginning of treatment?