51 results
To evaluate the contribution in terms of information provision and patients* perspectives of ICU-VR to prepare lung transplant patients for their future ICU admission
To demonstrate the clinical efficacy and safety profile of canaloplasty utilizing the iTrackTM Advance canaloplasty device performed via an ab-interno surgical technique achieves:1. Enhanced IOP reduction at 12 months due to the techniques ability…
The main objective of this study is to assess the feasibility, safety and (cost-)effectiveness of the HOME-ART intervention in comparison to regular hospital admission in patients with CA-ARTI.
To evaluate the effect of combined PVE/HVE compared to PVE alone on resectability and overall survival in patients with primary liver cancers.
The aim of this RCT is to examine the differences in functional, clinical, and radiological out-comes, between LCP fixation alone and femoral allograft augmentation in addition to LCP. Ultimately, the purpose is to optimize treatment strategies and…
The main objective is to replicate the results of the recent successful efficacy study on precuneus rTMS in AD by Koch et al. (2022). Secondary objectives include investigating what functional brain activity/network changes underlie the effects of…
The primary objective of the study is to investigate the medium to long term effects of replacing the conventional CXR exam with an ultra-low-dose CT in terms of patient health.Secondary outcomes are measures are • Quantity and type of follow-up…
The primary objective is feasibility of a prospective randomized trial, to investigate whether a more restrictive RBC transfusion strategy of 5.0 g/dL (3.1 mmol/L) is non-inferior compared to the current transfusion threshold of 7.0 g/dL (4.3mmol/L…
The primary objective of this study is to compare the effectiveness of two app-based interventions on diet quality and perceived stress compared to standard care.
This study aims to compare outcomes between ring augmented RYGB (RaRYGB) using the MiniMizer and standard RYGB without a ring.
In this study we aim to understand if (personalized) parenting tips strengthen parenting (e.g.: more structure, autonomy support, relatedness, less overparenting) and improve adolescent well-being (e.g.: higher life satisfaction, lower symptoms of…
The objective of the proposed study is to assess the effect of a combined lifestyle intervention for patients with cancer, who suffer from the consequences of cancer and its treatment, on Health-Related Quality of Life (HRQoL)
This study has been transitioned to CTIS with ID 2024-520305-39-00 check the CTIS register for the current data. Primary objective: to evaluate the efficacy of LSD 25µg every 3 days for 3 weeks in cCH. Additional objectives:- To evaluate the safety…
The objective of the study is to assess the effect of music on postictal agitation when played peri-interventionally for patients undergoing electroconvulsive therapy for severe depression.
The ultimate goal is to investigate whether aVNS can enhance cortical plasticity and improve functional outcomes during intensive rehabilitation programs in children with cerebral palsy. First, we aim to establish the extent of cortical plasticity…
Primary objectives:• To characterize the central inflammatory response to IV LPS by measuring biomarkers in CSF• To characterize the systemic inflammatory response to IV LPS by measuring biomarkers in blood • Characterize CSF/Blood ratios for each…
To investigate the effect of multiple sessions of whole body NMES, with or without consecutive protein intake, on muscle protein synthesis.
To compare L-MILP with R-MILP for benign and pre-malignant lesions of the pancreas in high-volume centers, regarding:1. Peri- and postoperative outcomes in terms of COMPOS-panc left score, for non-inferiority2. Total hospital-related costs, for…
The aim of this study is to compare the efficacy and safety of preoperatively placed Pericapsular Nerve Group block (PENG), Fascia-Iliaca Compartment Block (FICB) and Femoral Nerve Block (FNB) for patients with hip fractures in the ED.
The REPLACE study aims to determine whether not changing the catheter (catheter retained) for catheter-associated urinary tract infections (CAUTI)affects the recurrence-risk of CAUTI.