147 results
Primary objective: Inpatient Group: The primary objective of the research with the inpatient group is to assess whether there is a treatment effect in cognition (at T2) compared to baseline (T1) using conventional rehabilitation, as compared to…
This study has been transitioned to CTIS with ID 2024-512186-14-00 check the CTIS register for the current data. To assess benefits and harms of goal directed fluid removal with furosemide versus placebo on patient-important outcome measures in…
Test whether a mindfulness-based cognitive therapy intervention (MBCT) improves psychological distress, clinical symptoms, slows neurodegeneration, and/or enhances neuroplasticity in PD.
To improve the pathological response rate according to Miller and PayneTo improve quality of life including cognitionTo determine the effect of FMD on local tumor immunity
The objective is to evaluate the extent of lymph node dissection, efficacy, risks, quality of life and cost-effectiveness of RAMIE as an alternative to MIE as treatment for esophageal cancer.
The primary objective of the study is to assess the safety and efficacy of a pressure microcatheter guided treatment decision and PCI optimization compared to a pressure wire based strategy.
The main objective is to compare the accuracy of polyp size measurement by AccuMeasure to biopsy forceps assisted measurement. Secondary objectives are to assess: Reproducibility, precision of the measurements, time needed for measurement and…
Objectives: Primary: to determine whether SRT reduces the seizure frequency resulting in a reduction of at least 75% (RAEC I-III) in patients with drug-resistant focal epilepsy when compared to standard of care. Secondary: Assess quality of life (…
To determine the effect of tailored exergaming for inactive patients with HF to reduce their sedentary time, improve their daily physical activity, exercise capacity, decrease frailty and improve health-related quality of life.
This study has been transitioned to CTIS with ID 2024-515183-30-00 check the CTIS register for the current data. The aim of this prospective randomized, double blind study is to evaluate the analgesic effects of pre-operative PECS II-block with (…
To determine the effectiveness of the HEART (History, Electrocardiogram (ECG), Age, Risk factors, Troponin) score with POC hs-cTnI testing by ambulance nurses in safely ruling out ACS and increasing the number of patients left at home after…
This study has been transitioned to CTIS with ID 2024-518844-20-00 check the CTIS register for the current data. Primary Objective:To evaluate the efficacy of dapansutrile as an acute gout flare treatment compared to placebo in reducing joint pain…
Our primary objective is to investigate whether a personalised, physiotherapy intervention with integrated therapeutic virtual reality (VR) is (cost-)effective at 3 months and 12 months follow-up, compared to usual physiotherapy, in a subgroup of…
This study has been transitioned to CTIS with ID 2024-512300-19-00 check the CTIS register for the current data. The objective is to determine whether etidronate can halt or attenuate disease progression in patients with Fahr*s disease or syndrome.
The primary objective is to investigate the effect of a 3 week intervention with either 1.,3 gram or 2 gram of GOS on the abundance of the genus Bifidobacterium in faecal samples in healthy women of 40 - 70 years old. The secondary objective is to…
Primary objective: To show a meaningful reduction in progression of DD with the application of radiotherapy both in the early stages as well as following local treatment in the later stages.Secondary objectives: 1. Report physician graded toxicity…
To evaluate the added value of nCLE-imaging to conventional bronchoscopic peripheral lung lesion analysis on the diagnostic yield.
The primary objective of this study is to assess whether laser hair removal therapy improves the course and severity of mild to moderate HS, as assessed by the difference in IHS4 between groups over time between month 7 to month 12.
The primary objective is to compare the effectiveness of ambroxol versus placebo on the MDS-UPDRS part III motor sub-score in the *practically defined OFF-medication state* in patients with moderate PD, carrying a GBA mutation. The hypothesis is…
The primary objective of this study is to demonstrate the effect of consuming daily 5 grams of Agaricus bisporus powder (10 capsules) on the vaccination response to an influenza vaccine in men and women aged 60 years or older during the influenza…