143 results
This study has been transitioned to CTIS with ID 2024-512186-14-00 check the CTIS register for the current data. To assess benefits and harms of goal directed fluid removal with furosemide versus placebo on patient-important outcome measures in…
The present study proposes to investigate the On(t)schuldig intervention. The main research question: Do adolescents report less trauma-related feelings of shame and guilt after following the intervention On(t)schuldig?
Test whether a mindfulness-based cognitive therapy intervention (MBCT) improves psychological distress, clinical symptoms, slows neurodegeneration, and/or enhances neuroplasticity in PD.
To improve the pathological response rate according to Miller and PayneTo improve quality of life including cognitionTo determine the effect of FMD on local tumor immunity
The objective is to evaluate the extent of lymph node dissection, efficacy, risks, quality of life and cost-effectiveness of RAMIE as an alternative to MIE as treatment for esophageal cancer.
The primary objective of the study is to assess the safety and efficacy of a pressure microcatheter guided treatment decision and PCI optimization compared to a pressure wire based strategy.
The primary objective of this study is to assess the effect of ghrelin on the severity of the neurological deficit at seven days after symptom onset in patients with acute ischemic stroke caused by large vessel occlusion of the anterior circulation…
Objectives: Primary: to determine whether SRT reduces the seizure frequency resulting in a reduction of at least 75% (RAEC I-III) in patients with drug-resistant focal epilepsy when compared to standard of care. Secondary: Assess quality of life (…
Primary Efficacy Objective (Blinded Treatment Period)• To demonstrate the efficacy of rilzabrutinib versus placebo in participants with refractory/relapsed ITP, based on the durability of platelet response during the last12 weeks of the 24-week…
This study has been transitioned to CTIS with ID 2024-515183-30-00 check the CTIS register for the current data. The aim of this prospective randomized, double blind study is to evaluate the analgesic effects of pre-operative PECS II-block with (…
The purpose of this study is to determine if a diet lacking NEAA, with or without being replaced by additional EAA, influences skeletal muscle protein synthesis rates and whole-body metabolism in healthy young men.
To follow up on the previous study on PBM effects on well-being by prospectively assessing mood, drowsiness and depression as well as energy/tiredness/tension/calmness, and sleep parameters, and on health by prospectively assessing resting heart…
This study has been transitioned to CTIS with ID 2024-518844-20-00 check the CTIS register for the current data. Primary Objective:To evaluate the efficacy of dapansutrile as an acute gout flare treatment compared to placebo in reducing joint pain…
Our primary objective is to investigate whether a personalised, physiotherapy intervention with integrated therapeutic virtual reality (VR) is (cost-)effective at 3 months and 12 months follow-up, compared to usual physiotherapy, in a subgroup of…
This study has been transitioned to CTIS with ID 2024-512300-19-00 check the CTIS register for the current data. The objective is to determine whether etidronate can halt or attenuate disease progression in patients with Fahr*s disease or syndrome.
The current project investigates whether ILT-based exposure (strategies and techniques based on insights from ILT) leads to symptom reduction and is an acceptable treatment (for both patients and therapists). Additionally, we will examine whether…
Primary objective: To show a meaningful reduction in progression of DD with the application of radiotherapy both in the early stages as well as following local treatment in the later stages.Secondary objectives: 1. Report physician graded toxicity…
The current study investigates the effectiveness of an intervention that focusses on the adaptive emotion regulation strategy cognitive reappraisal for people with EDs in the reduction of anxiety. This intervention will be compared to a control task…
The primary objective of this study is to assess whether laser hair removal therapy improves the course and severity of mild to moderate HS, as assessed by the difference in IHS4 between groups over time between month 7 to month 12.
The primary objective is to compare the effectiveness of ambroxol versus placebo on the MDS-UPDRS part III motor sub-score in the *practically defined OFF-medication state* in patients with moderate PD, carrying a GBA mutation. The hypothesis is…