2446 results
The main objective of this study is to investigate the effect of a topically applied emollient enriched with barrier lipids on the barrier properties of skin of AE patients.
The primary purpose of the study is to determine the efficacy of AZD2281 compared to placebo in serous ovariancancer platinum sensitive patients and in a defined HRD subset.
The primary objective of this study is: To study the effect of controlled discontinuation of long-term used risperidone, for the treatment of challenging behavior, on behaviour and health. Our hypothesis is that long-term use of risperidone for…
The primary objective of this randomized clinical trial is to evaluate if perioperative SDD can reduce anastomotic leakage rate and other infectious complications while thereby simultaneously improving long-term oncological outcome. Secondary…
Primary Objective: The main objective is to investigate the effectiveness of PRT compared to CAU in school-aged children and adolescents with ASD.The primary research question is:1) Directly after treatment and at follow-up, what is the…
To provide further insight into Souvenaid*s hypothesised mode of action, the current NL-ENIGMA study explores brain glucose metabolism in mild cognitive impairment (MCI) and mild dementia due to AD, using Positron Emission Tomography with 18F-FDG-…
The primary objective of this pilot trial is to explore the difference between the intervention and control group in change from baseline (T0) to the end of therapy (T1) in therapy efficacy of the primary study outcome fatigue assessed by Checklist…
The present study focusses especially on the value of cognitive skill training within a program of work integration by means of IPS. Research shows that these interventions indeed lead to enhanced cognitive skills (Wykes et al. 2011). According to…
Primary Objective:What is the effectiveness of immediate opioid pain medication (followed by step-down) versus step-up pain medication within the treatment according general practitioners* clinical guideline in patients with (sub)acute sciatica,…
The purpose of this clinical study is to investigate surgical usability, patient-reported outcomes and effectiveness of the MaMaLoc technique and compare it with WGL.
The purpose of this research study is to evaluate how safe and effective Denosumab is, compared with placebo, in delaying the time it takes for cancer to spread to the bones in subjects with early-stage breast cancer at high risk of recurrence.The…
To investigate the effect of variations in the length of bilipancreatic limb on weightreduction in morbidly obese patients undergoing RYGB-surgery.
To investigate the efficacy of testosterone enhanced exposure therapy for social anxiety disorder.
BoneMaster ITo perform a comparative assessment between the clinical, bone remodelling, and radiographic outcomes (as measured with RSA) of the conventional Hydroxyl-Apetite (HA) Taperloc stem compared with Taperloc stem with additional BoneMaster®…
This study aims to enhance pharmacotherapeutic effects in patients with recent-onset RA by means of conditioning (via a variable reinforcement schedule).
To compare two surgical techniques in the treatment of patients with a anterior CECS.Surgical method 1: use of conventional *Due* fasciotome Surgical method 2: use of the new *Fasciomax©* in stead of the *Due*-fasciotome.
The objective of the LEOPARD-2 trial is to assess the safety of MIPD versus OPD and after that to assess the time to functional recovery of MIPD versus OPD for symptomatic benign, premalignant or malignant peri-ampullary disease.
To assess the effects on knee pain, function, quality of life and change in structural features with respect to cartilage and subchondral bone of osteotomy surgery after one year of follow-up compared to the effects of treatment with an orthopaedic…
The primary objective of the research is to measure the effect of a 3 week prehabilitation program on the postoperative complications in patients with an anaerobic threshold of <11 ml/kg/min who*ll undergo elective coloretal surgery for…
To investigate hearing improvement following day-case stapes surgery compared to in-patient stapes surgery and the effect of both methods on quality of life, cost-effectiveness and complication rates (mainly tinnitus and vertigo).