41 results
The primary objective of this pilot trial is to explore the difference between the intervention and control group in change from baseline (T0) to the end of therapy (T1) in therapy efficacy of the primary study outcome fatigue assessed by Checklist…
The purpose of this clinical study is to investigate surgical usability, patient-reported outcomes and effectiveness of the MaMaLoc technique and compare it with WGL.
In this study we would like to investigate the effect of CP (Peptan®) on pain, synovial inflammation and functional and clinical outcome parameters in patients undergoing total knee replacement therapy.
Hypothesis:Using PlasmaJet Surgical Device during surgery improves the rate of complete cytoreductive surgery in women with advanced ovarian cancer.Primary research question:Does the use of PlasmaJet technique result in an increased number of…
To investigate whether addition of amino acid-based nutritional supplements to FFED is more effective in reducing esophageal eosinophilic inflammation measured as reduction in absolute number of eosinophils than FFED alone, in adult EoE patients.
Primary objective: Assess the efficacy of Phantom Motor Execution (PME) aided by Myoelectric Pattern Recognition (MPR), Augmented and Virtual Reality (AR-VR), and Serious Gaming (SG) to reduce Phantom Limb Pain (PLP). Secondary objective: Assess the…
The main objective of this study is to examine the effect of EMDR as pre-treatment on psychological symptoms in patients with a PD. The secondary objective is to examine whether pre-treatment with EMDR still has an effect on symptoms three months…
To compare, in a randomized controlled clinical trial, titanium and zirconia implants for the replacement of a single upper premolar after 1 and 3 years of function.
The aim of the present study is to conduct a randomised controlled trial (RCT) to assess the effectiveness of a guided web-based transdiagnostic intervention in treating student depression and anxiety.
To assess the efficacy of haloperidol to resolve delirium in adult critically ill patients and thereby render the patient awake and non-delirious.
The primary goal of this study is to evaluate whether exposure in big steps is more effective than a small step-by-step approach. The secondary goal is to find child, parent and therapist factors that possibly relate to the effectiveness of the…
To assess the anabolic properties of key plant based protein sources and specific protein blends
Fujifilm Linked Color Imaging versus high-definition white light endoscopy for the detection of polyps in patients with Lynch syndrome.
Main-trial:Measuring the efficacy of once daily aspirin to inhibit platelet activity in patients during (recovery from) pneumonia or invasive urinary tract infection or cutaneous infection.Sub-study:To assess the influence of an infectious state on…
To evaluate the cost-effectiveness of a supportive bandage compared to cast for patients with a clinically suspected scaphoid fracture with normal initial radiographs. Our hypothesis is that patients with a clinically suspected scaphoid fracture…
In the present study, we aim to investigate the SUPPORT Coach as a tool to enhance traditional trauma-focused psychotherapy. Research questions concern:1. Potential improvement of trauma-focused therapy: Does usage of the SUPPORT Coach app in-…
1) Compare post-transfusion RBC clearance of fresh and stored RBCs and investigate whether glycolytic enzyme function, glycolysis, pentose phosphate pathway function and related metabolic pathways recover after transfusion of a 35 day stored RBC…
To evaluate the feasibility and clinical application of Virtual Reality (headmounted display and software) among sepsis survivors.
To demonstrate non-inferiority of oral fosfomycin-trometamol compared to oral ciprofloxacin as a step-down treatment for E.coli AF-UTI in women for the cumulative incidence of survival and clinical cure (resolution of symptoms) 6-10 days post-…
The aim of this study is to investigate the effect of the intranasal cooling (RhinoChill System) on the severity and frequency of withdrawal headache and associated symptoms in the first 7 days during standard care treatment for detoxification of…