108 results
Investigate whether the "Smarter Pregnant" intervention in comparison with four screenings with food- and lifestyle advising leads to an improvement in unhealthy food habits (vegetables, fruit, folic acid use) after 24 weeks intervention,…
To evaluate whether integral AF treatment in primary care is non-inferior in terms of reducing all-cause mortality (primary outcome) and specific cardiac mortality and hospitalization and non-cardiac hospitalization (secondary outcomes), as compared…
To investigate whether an adjunctive YBSR program added to standard care compared to standard care alone, can reduce:1.fatigue symptoms (primary objective)2.psychological distressand improve:3.health-related quality of life4.sense of coherence5.…
Our proposed randomized controlled trial is the first making this head-to-head comparison in a *real life* primary care setting in the Netherlands. The primary research question is: does a 12-week combination therapy of open label varenicline and…
This health care evaluation study will compare the ZPH with other, usual forms of care given to frail elderly in the hospital. It will also evaluate the added value of a centre for prevention and recovery (Centrum voor Preventie en Herstel, CPH)
The aim of the present study is to examine the effect of integrated telemonitoring and telecare, compared to usual care, on quality of life and hospitalization in patients with heart failure in primary care.PrimaryTo examine the effect of integrated…
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The research question of the main study is: What are the short- and long-term effects and costs of helmet treatmentcompared to a wait-and-see regimen for a period of 6 months on skull asymmetry in children withmoderate to severe DP.The objective of…
Main objectives: 1. to investigate the prevalence of vision abnormalities in 9- and 10 year old children; 2. to investigate the percentage of these vision abnormalities that were detected the VOV screening programme;3. to investigate whether these…
Main objective: to get insight in the effectivity of the SAM on depressive symptoms, quality of life, activity level, mastery and costs compared to treatment as usual in clinical admitted depressive elderly.Sedundary objective: to get an insight in…
The aim is to examine whether care and treatment guided by structural psychosocial screening leads to a better quality of life and greater patient satisfaction than usual care alone in patients with lung cancer.
The aim of the study is to investigate the added value of the *Routeplanner diabetespreventie*, compared to the usual care for people with an increased risk on diabetes.
1. To determine the level of cognitive, emotional and cardiorespiratory impairment, daily functioning, participation in society, quality of life and partner strain up to one year after the survival of a cardiac arrest.2. To determine prognostic…
The objective of this study is to improve the quality of care and outcomes for patients with anxiety disorders and depression and to acquire knowledge and insight into the effect of tailored strategies focused on the implementation of guideline…
To demonstrate that FS laser aided keratoplasty for KC is superior to MALK.
Study of the cost-effectiveness of fatigue management in patients with Crohn*s disease (CD)
The aim is to understand which individuals benefit from antibiotics.
If proven (cost)effective, without inducing antivral resistance, oseltamivir could have considerable benefits in this setting, although constraints relating to implementation need to be addressed as well. If not (cost)effective if this fragile…
To investigate if a dosage advice for darbepoetin and iron generated by a pharmacist leads to an increase of haemodialysis patients whose haemoglobin values lie within the target range, compared to dosage of darbepoetin by the nephrologist alone.
A pilot feasibility study (n=5) will be performed to evaluate the feasibility (logistics, timing) and safety of administering autologous tumor infiltrating lymphocytes (TIL) generated at the NKI-AVL infused in conjunction with systemic high-dose…