387 results
To explore cardiovascular remodelling with subsequent altered cardiac function (assessed as strain rate) in extremely premature neonates (born <30 weeks and/or birth weight < 1000 gram) with FGR.
Primary objective: Inpatient Group: The primary objective of the research with the inpatient group is to assess whether there is a treatment effect in cognition (at T2) compared to baseline (T1) using conventional rehabilitation, as compared to…
This study has been transitioned to CTIS with ID 2024-512186-14-00 check the CTIS register for the current data. To assess benefits and harms of goal directed fluid removal with furosemide versus placebo on patient-important outcome measures in…
The present study proposes to investigate the On(t)schuldig intervention. The main research question: Do adolescents report less trauma-related feelings of shame and guilt after following the intervention On(t)schuldig?
The main objective of this study is to assess patient reported outcome measures of adult patients who are diagnosed with a distal radius fracture and treated with a patient-specific 3D- printed splints as compared to a control cohort.
To determine the feasibility (main aim) and effectiveness (secondary aim) of a prehabilitation program in patients with HNC or liver cancer
Test whether a mindfulness-based cognitive therapy intervention (MBCT) improves psychological distress, clinical symptoms, slows neurodegeneration, and/or enhances neuroplasticity in PD.
To improve the pathological response rate according to Miller and PayneTo improve quality of life including cognitionTo determine the effect of FMD on local tumor immunity
The objective is to evaluate the extent of lymph node dissection, efficacy, risks, quality of life and cost-effectiveness of RAMIE as an alternative to MIE as treatment for esophageal cancer.
This study aims to demonstrate superiority of the research intervention (over standard of care) in [1] surgical success and [2] cost-effectiveness and non-inferiority in morbidity
Primary Objective study 1: The primary objective of study 1 is to explore the effectiveness of EMDR treatment targeting images of historic traumatic events in reducing the daily rated illness anxiety symptoms of patients with IAD.Primary Objective…
This study is aimed at understanding status and future cardiovascular disease (CVD) risk in UC outpatients in remission undergoing different anti-inflammatory therapeutic regimens (tofacitinib (a JAK1 - inhibitor), anti-TNF (infliximab or adalimumab…
The overall objective of the PRESTO-2 study is to evaluate the implementation of the Stroke Triage App, a decision support tool for individualized prehospital triage of patients with potential stroke.The specific objectives are the following:1)…
The primary objective of the study is to assess the safety and efficacy of a pressure microcatheter guided treatment decision and PCI optimization compared to a pressure wire based strategy.
The main objective is to compare the accuracy of polyp size measurement by AccuMeasure to biopsy forceps assisted measurement. Secondary objectives are to assess: Reproducibility, precision of the measurements, time needed for measurement and…
The objectives of this study are: 1. to identify new genetic variants causing or predisposing to PD; 2. to characterize the clinical phenotype in PD associated to specific genetic variants; 3. to investigate the molecular mechanisms of PD in…
Primary objective: To assess the effect of ICI on progression of coronary non-calcified plaque volume and ICI-related cardiovascular events by measuring differences in plaque burden using repeated CCTA.Secondary objectives:- To evaluate the relation…
The primary objective of this study is to assess the effect of ghrelin on the severity of the neurological deficit at seven days after symptom onset in patients with acute ischemic stroke caused by large vessel occlusion of the anterior circulation…
Objectives: Primary: to determine whether SRT reduces the seizure frequency resulting in a reduction of at least 75% (RAEC I-III) in patients with drug-resistant focal epilepsy when compared to standard of care. Secondary: Assess quality of life (…
To study the possible epigenetic modifications in sperm cells after BCG vaccination