1016 results
To investigate whether increased aldosterone levels in obese individuals lead to impairment of microvascular function through reduction of NO-availability, and to establish the role of microvasculaire dysfunction in the pathogenesis of salt-…
The effectiveness of PRP treatment in patients suffering from chronic lateral epicondylitis is still ambiguous. Therefore we study PRP treatment in a double blind randomized controlled trial in a homogeny patient population with respect to duration…
The main objective of this study is to investigate the effect of a single tDCS session in children with mild CP on different motor tasks. The second objective is to identify the optimal site of stimulation. In tDCS research the electrodes can be…
Primary objective of the study is to investigate whether Behavioral Activation for Negative Symptoms (BANS) improves negative symptoms. Secondary objective is to investigate whether effects of BANS on negative symptoms is mediated or moderated by…
To investigate if the active product shows a postprandial plasma triglyceride profile different from the control product in healthy adult male volunteers.
The focus of this pilot study is to investigate the results of a sialendoscopy (with or without rinsing with hydrocortisone 100mg) on the unstimulated whole mouth (UWS) and stimulated parotid (SP) (ml/min) flow of saliva, oral dryness, reported…
In the present study we will determine the effect of sympathetic blockade by TEA on major outcome parameters after off-pump CABG.
To test the cost-effectiveness of the psycho-educational intervention HypoBewust (HB) compared to care as usual.Research questions:1) Does HB significantly improve a) health related outcomes and b) societal costs after 6 months?2) Are the expected…
In the current research proposal, we aim to translate these preclinical findings to the human situation and test the hypothesis that MR antagonists limits IR-injury in human myocardial tissue. Secondly, we will test the hypothesis that the…
To evaluate the efficacy of 9mg budesonide/day and 3g mesalazine/day compared to placebo for the induction of remission in lymphocitic colitis.
1. To assess the efficacy of liraglutide in patients with schizophrenia and diabetes ona. Glycaemic controlb. Body weightc. Cardiovascular risk factors (blood pressure, lipids)2. To assess the safety of liraglutide in these patients3. To assess the…
Evaluation of the cosmetic result after 12 months of transcutaneous sutures versus intracutaneous sutures in the craniofacial area.
Demonstrate that with contemporary cardiac CT scan protocols good opacification of the coronary arteries can be achieved, that is similar to low-osmolar contrast media injected at the same iodine delivery rate. In addition, we will investigate the…
Primary objective: To determine the reduction of number of patients who receive blood transfusion perioperatively in the group pre-treated with erythropoietin and iron supplement compared to the control patients.
To compare the digestibility, bioavailability and subsequent muscle protein synthetic response to casein, with casein protein provided in an isolated manner versus casein in a milk matrix, in healthy elderly subjects
To investigate whether a specifically designed multispecies probiotic mixture (ecologic 825®), as adjuvant therapy, can contribute to an improvement of intestinal permeability, microbiota composition, disease activity and inflammatory markers in…
Main Objective:Assess the efficacy of eculizumab as compared with placebo in the treatment of refractory gMG based on the improvement in the MG specific Activities of Daily Living profile (MG-ADL).Secondary Objectives: - Safety and tolerability of…
Primary: To demonstrate the superiority of the insulin glargine/lixisenatide fixed ratio combination to insulinglargine in HbA1c change from baseline to week 30.Secondary: To compare the overall efficacy and safety of insulin glargine/lixisenatide…
The aim of this study is to investigate the cost-effectiveness of E-Exercise in comparison with usual care of a physical therapist. Research question for this RCT study is: What are the short- (3 months) and long term (12 months) (cost) effects of E…
The purpose of this study is to test the impact of a physical activity promotion program which is a personalized, semi-automated, coaching program utilizing an smartphone on which an app is installed and coaching by the investigator. The automated…