79 results
The study will help us to determine 1. the necessary type of (combined) examinations and 2. the sample size that is essential to evaluate (future) genetic therapy in Usher syndrome type 2 and USH2A associated nsRP.
Primary Objective: Assess which digital health metrics are relevant to monitor for patients with (or highly suspected of having) obstructive sleep apnea before and after diagnosis, and during titration of treatment with continuous positive airway…
Generation R studies growth, development and health from early pregnancy into adulthood. The study aims to contribute to the development of strategies for optimising health and health care across the full life course.
Generation R Next aims to examine the influence of preconception and pregnancy factors on growth, development and health of children from the earliest phase of life into young adulthood. The study aims to contribute to the development of strategies…
To develop a tailored care pathway for RDPC that ensures effective use for pregnant women in vulnerable circumstances.
Primary objective: To assess the long-term effect of treatment with lebrikizumab on the overall well-being in patients with moderate-to-severe AD using the WHO-5 questionnaire. Secondary objectives: To assess the clinical effectiveness of…
The aim of this study is to develop a Dutch adaptation and translation of the User Satisfaction Evaluation Questionnaire (USEQ), for measuring user satisfaction and usability in a Dutch pediatric population (6-18 years old), and to determine its…
The objective of this study is to evaluate the effectiveness of the STIL orthosis in people with dystonic tremor. In addition, we will investigate participants' satisfaction with the STIL orthosis. The results of this study will provide…
To gain insight in the facilitators and barriers for feedback to ED physicians about the diagnostic process
Whole genome comparison between microorganisms cultured from PJI and those cultured from preoperative swabs of the patients’ microbiome, to determine the origin of the infection.
To assess inter-individual and intra-individual variation in objective skin pigmentation measurement using non-invasive colorimetry and multispectral imaging in healthy individuals and patients with skin disease.
Primary objective 1: To understand how individuals with recurrent scabies symptoms experience the impact of scabies on their daily lives over time following a visit to the scabies clinic. Primary objective 2: To understand how individuals with…
The main objective of the study is to establish a controlled human infection model (CHIM) for RSV for future drug and vaccine testing and to identify the inoculation dose needed to induce RSV infection with this new strain in 50-70% of exposed…
The objectives of this pilot study are to obtain insight in: 1. healthcare visit behaviour of patients with recent onset hip or knee complaints; 2. patients’ barriers and facilitators to visit a primary healthcare professional…
The objective of this study is to pilot the feasibility of MRI and cine imaging in improving pre-operative staging of colon tumors. The specific aims of this pilot study are to establish an optimized scanning protocol and provide preliminary…
Primary objective: study the technical feasibility and safety to perform stereotactic radiotherapy on MR-linac for cT1-2 glottic cancer patients.Secondary objectives: monitor the patient safety, toxicity and tolerability of this…
This study aims to examine how senior year medical residents from different specialties in the Netherlands understand and apply the legal framework for reporting possible child maltreatment. Moreover, we aim to understand the threshold to report a…
[1] Mapping the demographic and clinical profile of pilots with (suspected) cardiovascular disease. [2] Investigating the role of non-invasive and invasive diagnostics within the treatment pathway of pilots with cardiovascular disease. [3]…
We have recently implemented ultrarapid genetic testing using Nanopore long-read genome sequencing (LR-GS) at Erasmus MC to guide treatment and enhance outcomes in urgent care scenarios. In this study, we aim to retrospectively…
The aim of this study is two-fold. First, we will test a newly developed VR environment that is able to adjust to real-time physiological parameters indicative for stress such as heart rate and heart rate variability and its effects on…