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Paediatric distal radius torus fracture treatment comparison in a prospective randomized control trial: mitella versus plaster cast

If the study shows that the treatment with a sling gives an earlier return to normal function en does not give a clinically significant difference in pain experience compared to cast therapy than the traditional treatment can be adjusted. We aim at…

Implementing Treatment Algorithms for the Cure of Trauma Induced Coagulopathy (iTACTIC)

The primary objective is to compare the haemostatic effect of VHA-guided transfusion strategy versus optimized CCT guided transfusion strategy in haemorrhaging trauma patients. The secondary objectives of the study are to determine the effects of…

A multicenter, multinational, randomized, controlled, open label study, performed in children with thermal burns, to evaluate the efficacy and safety of NexoBrid as compared to standard of care (SOC) treatment

To evaluate the safety and clinical benefit of NexoBrid in hospitalized children (0-18 years) with deep partial and/or full thickness thermal burns of 1-30% TBSA and to compare NexoBrid to standard of care (SOC).

Evaluation of different wound dressings in the treatment of children with spoke injuries

To study wether a biodressing impregnated with polyhexamethylene biguanide in the treatment of spoke injuries in children could give a reduction in pain during the treatment compared to the standard treatment with wound dressing impregnated with

Clinical Application of a Dermal Substitute based on glycerol
preserved Allograft: GLYADERM®
A multicentre, prospective, controlled, randomized, comparative
trial of Glyaderm® and split thickness skin graft versus split
thickness skin graft alone in full thickness skin defects

Objective: The main objective is to evaluate the difference in scar quality, after skin restoration of full thickness defects treated with Glyaderm® and STSG versus STSG alone.Secondary objectives are: to evaluate the percentage of Glyaderm® take…

*Unilateral fracture of the mandible: a comparison of intermaxillary fixation with screws or arch bar*

The aim of the present study is to demonstrate the effectiveness of screw IMF.

Cost-effectiveness of laser Doppler imaging in burn care in the Netherlands

To gain insight in the effects and cost-effectiveness of the introduction of laser Doppler imaging in burn care.

UNA PATELLA PARTICULARE
Patellar resurfacing in total knee arthroplasty: a randomized controlled clinical trial

Primary outcomeThe primary objective of the study is to evaluate if patients undergoing resurfacing of the patella during TKA show at least 10 % improvement in the Baldini score (after 24 months) compared to patients undergoing TKA without…

Epiglottic downfolding during endotracheal intubation* An alternative technique to improve glottic exposure, and facilitate intubation?

We want to determine if epiglottic downfolding leads to a better view of the glottis and more successful intubations. We also want to investigate if this comes at the cost of more postoperative sore throat, dysphonia, dysphagia and coughing…

Paracetamol or NSAID's in acute musculoskeletal syndromes

The objective of the current study is to compare three different strategies of pain management in patients presenting to an emergency department and to a general practice with acute musculoskeletal syndromes (defined as musculoskeletal complaints…

Game Ready continuous-flow cryo- and cyclic compression therapy after fracture treament of the hip: a prospective multicenter, open-label, multicenter, randomized, controlled, clinical trial on postoperative effects on pain.

The goal of the study is whether to establish if application of combined cyrocompression therapy directly postoperative after hip fracture surgery results in a significant reduction in painperception en whether this reduces the morfine consumption.…

Anticoagulant treatment after knee arthroscopy or during plaster cast lower leg immobilisation: determining the balance between benefits and risks

Comparative effectiveness research to determine cost-effectiveness of an existing healthcare policy, i.e. treatment with low molecular weight heparin (LMWH) after knee arthroscopy and lower leg plaster cast immobilization following surgical or…

Gauze throat at Oropharyngeal surgery

To investigate postoperative nausea and vomting in patients with or without a gauze throat after an operation of the mouth

A multicenter randomized controlled trial comparing long term scar quality after hydrosurgical versus conventional tangential excision of deep dermal burns

To assess and compare long term scar quality of deep dermal burns after debridement with hydrosurgical- and conventional tangential excision.

Conservative treatment of a complete rupture of the ulnar collateral ligament of the thumb

to investigate whether applying a conservative treatment for an unstable ligamentous skiers thumb is equal to surgical repair.

Decongestants for dilating the nasal cavity, a randomised, blinded, prospective study to prevent iatrogenic epistaxis during nasotracheal intubation

Primary Objective:The purpose of this study is to investigate the clinical efficacy of xylomethazoline, combined with dilating the nasal passage way with a polyvinyl-alcohol nasal dilator in the prevention of iatrogenic epistaxis during nasotracheal…

Local gentamicin in Redon treated post-sternotomy mediastinitis

The aim of our study is to evaluate clinical outcomes of patients primarily closed over Redon catheters for the treatment of PSM, comparing the application of local gentamicin with a control group.

Use of the Auditory Biofeedback system to improve a patient*s partial weight bearing compliance: a feasibility study

Primary Objective: To determine whether it is feasible to use an ABF device to lower the amount of incorrect steps. Incorrect steps are the steps exceeding the maximum allowed load or being below the minimum load.The specific research question that…

The development and examination of an intervention aimed at youths who have to be treated at the emergency department of a hospital as a result of excessive alcohol use.

Aim of the study is to develop and test a brief intervention for adolescents who have to be treated in the emergency department of a hospital due to excessive alcohol use.

Same level fibular plating versus not plating in distal metaphyseal tibia fractures treated with intramedullary nails: a randomized trial.

Primary question:I. Does additional fibular plating lower the incidence of malalignment after surgical treatment of distal same level metaphyseal tibia and fibula fractures treated with locked intramedullary nailing?Secondary questions:I. Does…