The aims of this research project are to: (1) Provide clinimetric data (on validity, reproducibility, consistency) for the NISPA SUMID Questionnaire into substance use in this population. (2) Establish population prevalence rates of alcohol, tobacco…
ID
Source
Brief title
Condition
- Other condition
Synonym
Health condition
gebruik van psychoactieve stoffen
Research involving
Sponsors and support
Intervention
Outcome measures
Primary outcome
Validation study
Validity of SUMID Self Report and Collateral Report Questionnaire: Sensitivity
and specificity of the SUMID Self Report and Collateral Report for detection of
substance use will be calculated for each substance (tobacco, cannabis,
alcohol, cocaine), and for 2 reference periods (last month, recent use),
against positive biomarkers (BAC, hairanalysis, urinalysis, plasteranalysis).
Convergent validity between Self Report and Collateral Reports will be
calculated using chi-square tests. Test-retest reliability will be assessed
calculating kappas. Internal consistency for section 2 (knowledge of and
attitudes towards substances) and section 4 (consequences of substance use and
motivation to change) will be assessed aiming at a Cronbach*s alpha of at least
.80. For dichotomous knowledge items the Kuder-Richardson-20 coefficient
(Nunnally 1994) will be calculated. In order to establish construct validity of
the knowledge, attitude and consequence scales factor analysis will be
calculated.
Relationships between knowledge, attitude and consequence subscales and
substance use will be assessed by multiple logistic regression methods.
Sociodemographic risk factors will be found by comparing sociodemographic
differences between non-users, and users using Multivariate Analysis.
ROC curves will specify optimal cut off values for the scores on knowledge,
attitude and consequences, to differentiate between problematic users, users
and non-users. Pearson correlations will be used to establish relations between
knowledge, attitude, and consequences scales.
ANOVA and GLM will be used to test whether the combined knowledge, attitude and
consequence means differ for specific groups depending on for instance living
and working arrangements, gender or age groups.
Prevalence Study
Population prevalence of substance use will be calculated from NISPA SUMID Self
Report and Collateral Report Questionnaires. Data will be summarized by
producing frequency tables and descriptive statistics.Finally, sociodemographic
characteristics of subjects who were not willing to participate in this study
will be compared with those who did (analysis of non-response).
Secondary outcome
n.a.
Background summary
About 6-8% of the general population has mild or a borderline Intellectual
Disability (ID), defined as an IQ below 80 and significant impairment of
adaptive/social functioning. Subjects with ID may have an increased risk for
psychopathology and substance misuse, in particular of alcohol and cannabis.
They are further at increased risk for the negative consequences of substance
misuse, in terms of somatic, psychological and social complications. Due to the
current focus on outpatient services and closing down of inpatient services for
subjects with ID, substance misuse among this population seems even to have
risen over time. Health care professionals face serious obstacles when trying
to diagnose and treat substance misuse in subjects with ID (SUMID). This is due
to a lack of data about the real scope of SUMID, that is about its prevalence,
and about its demographic, social, cognitive and psychopathological
determinants. Further, there is a lack of knowledge about valid and appropriate
instruments for screening and diagnosing SUMID and effective interventions.
Information about substance misuse obtained by self-report in subjects with ID
is less reliable than in subjects with normal intellectual abilities.
Study objective
The aims of this research project are to:
(1) Provide clinimetric data (on validity, reproducibility, consistency) for
the NISPA SUMID Questionnaire into substance use in this population.
(2) Establish population prevalence rates of alcohol, tobacco, cannabis,
cocaine use in a Dutch population of Intellectually Disabled Adults
(3) Identify socio-demographical determinants of risks of substance-related
problems in this population
(4) Provide insight in knowledge of, and attitudes toward and consequences of
substance use by persons with ID, and the relations between these factors and
substance use
(5) Identify the population at risk for substance use
Study design
This study into Substance Use and Misuse in Intellectual Disability comprises 2
parts:
1. Validation study of the NISPA SUMID Questionnaire using biomarkers as the
golden standard for recent (urinalysis) and long term (hairanalysis) use in a
subpopulation with high risk of substance use.
2. Cross-sectional multistage clustered sampling survey with the NISPA SUMID
Questionnaire of the ID population receiving care by social services associated
in the VGN (Vereniging Gehandicaptenzorg Nederland, Dutch Association of Social
Services for ID).
Study burden and risks
The burden of participation in this project are restricted to a minimum:
- measuring of breath alcohol content by a handheld device
- one session with a research assistent to fill out the SUMID questionnaire
- providing an urine and hair (and/or plaster) sample (this only applies to the
participants in the validation study)
Institutenweg 1
7521 PH Enschede
Nederland
Institutenweg 1
7521 PH Enschede
Nederland
Listed location countries
Age
Inclusion criteria
- adults (18+) receiving care (sheltered living intensive or low intensity form, sheltered working, outreaching help, full inpatient care), by professional careproviders (selected from VGN network)
- Willing and consenting to participate, and with consent of caregiver or family member
Exclusion criteria
- <18 yrs
- No ID (IQ tested above 80 or education level implying normal intelligence). This may apply to some of the clients of participating services who receive care mainly for other developmental disabilities (eg autism)
- Not willing or consenting to participate
- Not able to participate (due to severe ID (IQ <50) , severe other health issues, severe language or other communication barriers such as severe autism)
Design
Recruitment
Followed up by the following (possibly more current) registration
No registrations found.
Other (possibly less up-to-date) registrations in this register
No registrations found.
In other registers
| Register | ID |
|---|---|
| CCMO | NL27716.044.09 |