No registrations found.
ID
Source
Health condition
Vitamin D suppletion
aspecefic musculoskeletal disorders
allochtone
Vitamine D suppletie
Aspecefieke klachten van het bewegingsapparaat
Niet-westerse allochtonen
Sponsors and support
Intervention
Outcome measures
Primary outcome
Differences in improvement of pain as assessed by questionnairies at week 0
and 6 (between placebo- and vit D3-group)
Secondary outcome
1. Differences in improvement of pain as assessed by questionnairies at week 12
(between 150.000and 300.000-vit D3-group);
2. Serum 25-OH-D levels at week 12 (150.000 and 300.000 group);
3. Differences in improvement of pain as assessed by questionnairies at week 6
and week 12 (between placebo-vit D3-group and vit D3-placebo-group);
4. Serum 25-OH-D levels at week 12 (placebo-vit D3-group and
vit D3-placebo-group);
5. Correlations between localisation of complaints, improvement of pain as
assessed by questionnairies, initial serum 25-OH-D levels and serum 25-OH-D
levels at week 12.
6. Differences in ability to walk stairs as assessed by questionnairies at week 6 and 12 between placebo and vitamin D group
Background summary
In several primary health centers placebo or (1-2x) 150.000 IU will be given to Vit D deficient patients with aspecific musculoskeletal disorders. Questionairies i will show wheter this helps them or not
Study objective
Vitamin D suppletion can relief aspecefic musculoskeletal disorders in allochtone patients.
Intervention
150.000 IU vit D3 or placebo in one oral gift at week 0
Idem at week 6 (but: if given placebo at week 0,one will allways get vit D3)
Inclusion criteria
1. Asian en African men and women, visiting their general practitioners;
2. 18-60yrs;
3. > 13 weeks aspecific musculo-skeletal disorders (i.e. musculoskeletal
complaints without a specific cause like:
a. trauma or infection or;
b. localisation (like gonarthrose) or; complex of symptomes (like HNP,
polymyalgia rheumatica).
Included are for instance low-backpain,
fibromyalgia, fasciitis plantaris. Depression is NOT an exclusioncriterium.
4. Serum 25OHD level < 50nmol/ml.
Exclusion criteria
1. Pregnancy;
2. Vitamin D suppletion in the last 4 months;
3. Rachitis;
4. Renal insufficiency;
5. Sarcoidosis;
6. TBC;
7. Peanut-allergy;
8. Use of cyclosporines, statines or oral steroids.
Design
Recruitment
Followed up by the following (possibly more current) registration
No registrations found.
Other (possibly less up-to-date) registrations in this register
No registrations found.
In other registers
| Register | ID |
|---|---|
| NTR-new | NL944 |
| NTR-old | NTR970 |
| Other | : |
| ISRCTN | ISRCTN54027991 |
Summary results
Ferdinand Schreuder, MD1 Roos M. D. Bernsen, PhD2
Johannes C. van der Wouden, PhD1.<br>
ANNALS OF FAMILY MEDICINE ✦ WWW.ANNFAMMED.ORG ✦ VOL. 10, NO. 6 ✦ NOVEMBER/DECEMBER 2012.