To determine the prevalence of posttraumatic osteoarthritis following a PLD-PLFDs in a cohort of young non-osteoporotic patients and correlation with objective and subjective outcome measures.
ID
Bron
Aandoening
posttraumatic osteoarthritis
perilunate dislocation/fracture
outcome
Ondersteuning
C.M.Lameijer
C.K. van der Sluis
Onderzoeksproduct en/of interventie
Uitkomstmaten
Primaire uitkomstmaten
The prevalence of posttraumatic osteoarthritis.
Achtergrond van het onderzoek
The development of posttraumatic osteoarthritis (PA) following perilunate dislocations and perilunate fracture dislocations (PLD-PLFDs) has been described. Direct and indirect joint impact loading, soft tissue injuries, joint dislocation and intra-articular fractures, increase the risk of progressive joint degeneration that cause PA. It is though posttraumatic osteoarthritis develops less in younger patients. However, it might be more invalidating for a young non-osteoporotic patient to develop posttraumatic osteoarthritis and loss of function following PLD-PLFD than for an older patient. The extent of the loss of function can be objectified using functional measures, such as range of motion and grip strength. Subjective measures to objectify loss of function as experienced by the patient can be performed using validated questionnaires. In this study, the prevalence of posttraumatic osteoarthritis following a PLD-PLFD in young patients is determined. Also, the question arises what the correlation between objective and subjective outcome measures is following a PLD-PLFD in young patients.
Doel van het onderzoek
To determine the prevalence of posttraumatic osteoarthritis following a PLD-PLFDs in a cohort of young non-osteoporotic patients and correlation with objective and subjective outcome measures.
Onderzoeksopzet
Observational study, there will be various timepoints.
Onderzoeksproduct en/of interventie
No intervention.
Questionnaires: PRWE, DASH, SF-36 and MHQ.
X-rays of both hands. Range of motion test and grip strength test by a certified handphysician
Publiek
Hanzeplein 1
C.M. Lameijer
Groningen 9713 GZ
The Netherlands
+31628425094
C.M.Lameijer@umcg.nl
Wetenschappelijk
Hanzeplein 1
C.M. Lameijer
Groningen 9713 GZ
The Netherlands
+31628425094
C.M.Lameijer@umcg.nl
Belangrijkste voorwaarden om deel te mogen nemen (Inclusiecriteria)
All patients treated in the period 1996 until 2014 in the University Medical Center Groningen for a PLD-PLFD
- Men between the ages of 18 - 50 years and women between the ages of 18 - 40 years at the time of injury (no clinical osteoarthritis according to current available information in the literature)
- Written informed consent
- Mentally competent
Belangrijkste redenen om niet deel te kunnen nemen (Exclusiecriteria)
Preexistent osteoarthritis of the hand or preexistent declined function of the hand or wrist according to the patient
- ASA III-V patients or other contra-indications for surgical treatment at the time of injury. These patients are not able to receive the most optimal treatment and thus altered outcome measures can be expected
- No permanent residency (in the Netherlands)
- Co-morbidity that may influence the outcomes, such as neurological of rheumatic disorders influencing arm function.
- Insufficient control of the Dutch language.
- No informed consent
- Osteoporosis known from medical history
- Pregnant women
Opzet
Deelname
Opgevolgd door onderstaande (mogelijk meer actuele) registratie
Andere (mogelijk minder actuele) registraties in dit register
Geen registraties gevonden.
In overige registers
Register | ID |
---|---|
NTR-new | NL5316 |
NTR-old | NTR5425 |
CCMO | NL52111.042.15 |
OMON | NL-OMON44129 |